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New Research: How Gut Microbes May Help Regulate Blood Sugar and Liver Health
A new study in Cell Metabolism has found that a natural compound made by gut bacteria - called D-lactate - may play an important role in controlling blood sugar and reducing fatty liver disease.
Researchers discovered that when D-lactate builds up in the bloodstream, it can help the body manage glucose levels and fat metabolism more effectively. In animal studies, adjusting D-lactate activity improved both blood sugar control and liver health, especially in obesity-related conditions.
This breakthrough points to the gut microbiome as a powerful new target for preventing and managing metabolic diseases such as type 2 diabetes and non-alcoholic fatty liver disease (NAFLD).

Original research: https://www.cell.com/cell-metabolism/fulltext/S1550-4131(25)00328-6?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1550413125003286%3Fshowall%3Dtrue